You need to ensure that you have the best spot in the room to present from. There are various aspects to consider when you decide what is the best place to stand for your presentation. You also need to consider if you stand in one spot or move around during your presentation.
One of the aspects to consider for your presentation is the light. You obviously need to stand in the spotlight, but there are more considerations. For example when there are windows on one sight of the room and you have the option to stand on both sides of the room (having the windows on your left or right side). If your audience needs to take notes you can consider having the windows on the left side of your audience. Most people are right handed and in this case there is no shadow from the light from outside if your audience has the windows on their left side.
